Wicherts et.al. (
Wicherts. 2010) published the results of an investigation into the effectiveness of a) sun exposure or b) supplementation with daily 800 IU or 100,000 IU once in three months on serum 25(OH)-D3 levels in 211 otherwise healthy non-western immigrant in the Netherlands. As you can see in table 1, the initial high dose of 100.000 IU raised 25(OH)D levels significantly faster but to a lower extent than the 800 IU daily dosing:
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Table 1: Proportion (%) of participants with serum 25(OH)D<25, 25−50, 50−75, or >75 nmol/l at baseline, 3, 6, and 12 months according to treatment group 800 IU/day, 100,000 IU/3 months or sunshine exposure (Wicherts. 2010. Table 2) |
Otherwise, Wickerts' study confirms the results of earlier investigations,
mean serum 25(OH)D increased to 53 nmol/l with 800 IU/day, to 50.5 nmol/l with 100,000 IU/3 months, and to 29.1 nmol/l with advised sunlight exposure.
Though, even according to the "old" reference ranges, a 25(OH)D level <30 nmol/l does not ascertains a sufficient supply with a vitamin the importance of which scientists come to realize only in the last couple of years. Wicherts would thus not only have to conclude that
[...] Vitamin D supplementation is more effective than advised sunlight exposure for treating vitamin D deficiency in non-western immigrants,
but also, that vitamin D supplementation is indicated in non-western (dark skinned) immigrants to the northern hemisphere, where sun exposure is limited and insufficient to provide them with sufficient amounts of vitamin D.
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